DEV Koromila Lab DEV

koromila_hero

Welcome to Our Lab!

Epigenetic Regulation of Gene Expression

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam.

koromila_hero

Welcome to Our Lab!

Epigenetic Regulation of Gene Expression

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam.

koromila_hero

Welcome to Our Lab!

Epigenetic Regulation of Gene Expression

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam.

Research

How does a gene, consisting only of a string of DNA nucleotides, know when it should express itself? How do different types of cells know
which proteins to produce?

The answers to such questions lie in the study of dynamic
gene expression.

The Koromila lab combines Super Resolution Live Imaging and whole genome approaches with single-cell sensitivity to visualize transient molecular events and to study how changes in gene expression can drive cell identity over time.

Understanding Transcriptional Dynamics In Embryos

Uncovering Gene Expression Regulation in Bone Metabolism

Spatiotemporal
Protein Manipulation
with Blue Light

Publications

Lorem ipsum dolor sit amet, consectetur
adipiscing elit, sed do eiusmod tempor incididunt
ut labore et dolore magna aliqua. Ut enim ad minim
veniam, quis nostrud exercitation ullamco laboris
nisi ut aliquip.

publications_img

Fenelon, K., Krause, J., Koromila, T.

Opticool: Cutting-edge transgenic optical tools.

PLOS Genetics (2024)

Fenelon, K., Gao, F., Borad, P., Abbasi, S., Pachter, L., Koromila, T.

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos.

Frontiers in Cell & Dev Biol (2023)

Fenelon, K., et al.

Transgenic Force Sensors and Software to Measure Force Transmission across the Mammalian Nuclear Envelope in Vivo.

The Company of Biologists, (2022)

Fenelon, K., Krause, J., Koromila, T.

Opticool: Cutting-edge transgenic optical tools.

PLOS Genetics (2024)

Fenelon, K., Gao, F., Borad, P., Abbasi, S., Pachter, L., Koromila, T.

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos.

Frontiers in Cell & Dev Biol (2023)

Fenelon, K., et al.

Transgenic Force Sensors and Software to Measure Force Transmission across the Mammalian Nuclear Envelope in Vivo.

The Company of Biologists, (2022)

Fenelon, K., Krause, J., Koromila, T.

Opticool: Cutting-edge transgenic optical tools.

PLOS Genetics (2024)

Fenelon, K., Gao, F., Borad, P., Abbasi, S., Pachter, L., Koromila, T.

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos.

Frontiers in Cell & Dev Biol (2023)

Fenelon, K., et al.

Transgenic Force Sensors and Software to Measure Force Transmission across the Mammalian Nuclear Envelope in Vivo.

The Company of Biologists, (2022)

Fenelon, K., Krause, J., Koromila, T.

Opticool: Cutting-edge transgenic optical tools.

PLOS Genetics (2024)

Fenelon, K., Gao, F., Borad, P., Abbasi, S., Pachter, L., Koromila, T.

Cell-specific occupancy dynamics between the pioneer-like factor Opa/ZIC and Ocelliles/OTX regulate early head development in embryos.

Frontiers in Cell & Dev Biol (2023)

Fenelon, K., et al.

Transgenic Force Sensors and Software to Measure Force Transmission across the Mammalian Nuclear Envelope in Vivo.

The Company of Biologists, (2022)

Jobs

We are hiring
at all levels

If you are excited to disentangle the complexities of gene regulation with imaging and computational tools, apply!